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According to reprints

Product name: Periplaneta americana Linnaeus

Properties: brown powder

Nature, taste and meridians: cold, salty, liver, spleen, kidney meridians.

Function and indications

Dissipate blood stasis, detoxify and eliminate chancre, diuretic and detumescence. It is used for conglomeration accumulation, infantile malnutrition, beriberi edema, furuncle, swollen poison and insect snake bite.

 

Anti-tumor

Oral mucosa repair, digestive tract ulcer: can speed up the repair of digestive tract mucosa is often used as a supplement to protect digestive tract mucosa.

Sore: It can reduce the edema of wound tissue, promote the proliferation of wound granulation tissue, and accelerate wound healing.

It can effectively improve immunity, protect the liver, and promote tissue repair.

 

Materia medica records

"Shennong Herbal Classic" : main blood stasis, disease, cold and heat, break accumulation, throat and pharyngeal bi.

Tang Bencao: Qi under eating.

"Compendium of Materia Medica" : main blood stasis, disease, cold heat, Qi, blood.

"Classification of Herbal nature" : cure all dietary toxins. The same centipede pound package fish mouth, eliminate sores, compress poison, treat throat moths.

"Luchuan Materia Medica" : dispelling wind and relieving heat, promoting blood flow. Treat swelling (external application).

Modern pharmacological research

 

Antitumor effect

In vitro, the ethanol extract of Periplaneta Americana can be used to treat chronic myeloid leukemia (K562), promyeloid leukemia (HL60), mouse leukemia (P388D1) cell lines, nasopharyngeal carcinoma (CNE), lung cancer (A549), oral epithelial carcinoma (KB) cell lines. Ovarian cancer (HO8910), cervical cancer (Hela) and prostate cancer (PC3) cell lines, esophageal cancer (Ecal09), gastric adenocarcinoma (BGC823), colon cancer (LS174T) cell lines had growth inhibition. In vitro, the inhibitory effect on BGC823 cells was similar to that of cisplatin (DDP), and showed a time - and dose-dependent anchor.

The extract of Periplaneta Americana can inhibit the growth of Lewis lung cancer and 3LL lung cancer in mice, and promote the apoptosis of tumor cells.

 

Improve immune function

The American cockroach meal not only has a non-specific immunomodulatory effect on the immunocompromised mice caused by cyclophosphamide, but also has a positive effect on both cell-specific immunity and humoral immunity.

 

Hepatoprotective effect

Both water extract and water stirred extract of Periplaneta Americana had protective effects on CCL4-induced liver injury in mice.

 

Promotes tissue repair

The extract of Periplaneta Americana can significantly promote the proliferation of granulation tissue in wound and burn models of mice, and there is a corresponding dose-effect relationship.

The extract of Periplaneta Americana can significantly promote wound healing in rabbit wound, burn and ulcer models.

The extract of Periplaneta Americana showed significant protection against acute ulcer and ethanol-induced gastric mucosal injury in mice.

The American cockroach meal can reduce the content of MDA in the serum of diarrhea mice, and increase the activity of SOD, GSHPX and TAOC, so as to effectively antagonize the damage of free radicals to the body. In addition, it can not only reduce the number of intestinal Escherichia coli, but also repair the intestinal mucosa and villi that have undergone pathological changes.

 

Analgesic effect

The extract of Periplaneta Americana could inhibit the ear swelling caused by benzene, the foot swelling caused by egg white, reduce the number of body twisting caused by acetic acid, and increase the pain kan of hot plate method.

 

Species of American cockroach powder

Original powder: Blattella superfine powder, without any processing only dried and crushed.

Defat powder: improved by degreasing, deoiling and other professional degreasing technology, improve odor acceptance, taste, taste is more acceptable than the original powder.

American cockroach extract: Brown or reddish-brown liquid extract; No odor, slightly fishy, low temperature (below 0℃), sealed, away from light, sterile storage.

Extract concentrated powder: that is, freeze-dried powder, high production cost, strong water absorption, not easy to save, high price, not recommended for customers to use.